Is Medusa Cucina Siciliana open on Mondays?

Yes — Medusa Cucina Siciliana is open Monday from 5:00 PM to 11:00 PM.

Where is Medusa Cucina Siciliana?

Medusa Cucina Siciliana is at 644 Selden St, Detroit, MI 48201.

Does Medusa Cucina Siciliana do takeout or delivery?

According to its Google listing, Medusa Cucina Siciliana offers takeout and does not offer delivery.

Does Medusa Cucina Siciliana take reservations?

Yes — Medusa Cucina Siciliana accepts reservations.

What is the phone number for Medusa Cucina Siciliana?

You can reach Medusa Cucina Siciliana on +1313-798-3498.

Medusa Cucina Siciliana

Name: Medusa Cucina Siciliana
Address: 644 Selden St, Detroit, Michigan, 48201, US
Telephone: +1313-798-3498

4.7(172)· GoogleItalian Restaurant Midtown

Closed · opens 4:00 PM

(313) 798-3498 Directions medusa-detroit.com

Quick facts

Medusa Cucina Siciliana is a italian restaurant at 644 Selden St in Detroit, MI, open Sun–Sat from 4:00 PM. takeout, dine-in and reservations available.

Address: 644 Selden St, Detroit, MI 48201
Phone: +1313-798-3498
Hours today: 4:00 PM – 11:00 PM
Accessibility: Wheelchair accessible entrance

About Medusa Cucina Siciliana

Medusa Cucina Siciliana is a women-owned Italian restaurant at 644 Selden St in Detroit, MI, with a focus on Sicily’s culinary heritage. The restaurant describes its approach as honoring the island’s layered history and the culinary influences left by its different rulers. Dinner offerings include small plates, comfort food, and vegan and vegetarian options, with dessert and late-night food also available. An on-site bar serves wine, cocktails, beer, and liquor, and coffee is offered as well.

The setting is described as cozy and romantic, with both casual and upscale elements. Medusa accepts reservations and offers table service, outdoor seating, takeout, and a private dining room; delivery is not available. It welcomes families and groups and is also listed as suitable for solo dining. The entrance, seating, and restroom are wheelchair accessible, though wheelchair-accessible parking is not listed as available. Paid street parking is available. The restaurant has a Google rating of 4.7 from 172 reviews.

Known for

Sicilian culinary focus
Wine, cocktails, and an on-site bar
Vegan and vegetarian options
Private dining room and outdoor seating
Women-owned restaurant

Good for

Patio seating
Open late
Good for groups
Takes reservations
Takeout
Dine-in
Wheelchair accessible

What reviewers say elsewhere

“We came in for our 8PM reservation at the bar only to be told to wait because people who were waiting for their non-bar tables were in the seats and they couldn’t move them. Fine. We sat down about 20 minutes past 8PM. We did the tasting…”
— Gretchen Sauer, September 12, 2026 · google
“Great new Sicilian restaurant with true Sicilian dishes...great drinks great staff”
— Tom Corsentino, September 12, 2026 · google
“We loved Medusa! The vibe is relaxed, the restaurant is beautiful, and the service was exceptional. The menu size is perfect. Everything we tried was full of flavor. You can really taste how fresh the ingredients are, and the food is cre…”
— Sheila Sungurlu, September 11, 2026 · google
“Oh. My. God. Just when we thought Chef Anthony couldn’t do better than SheWolf, Medusa comes along. The food was so authentically Sicilian and absolutely perfect. Red, the Somm and Brandon our waiter went above and beyond. We did the t…”
— Halie Stutz, September 11, 2026 · google

Excerpts are shown for attribution and remain the property of their source.

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